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Sustained Expression of Pre-TCR Induced β-Catenin in Post-β-Selection Thymocytes Blocks T Cell Development

Pre-TCR and IL-7R signals regulate β-selection of thymocytes and then must be down-regulated for further development. However, the molecular events that control down-regulation remain unknown. We and others have previously shown that β-catenin in cooperation with TCF regulates β-selection. In this p...

詳細記述

保存先:
書誌詳細
主要な著者: Xu, Mai, Sharma, Archna, Hossain, M. Zulfiquer, Wiest, David L., Sen, Jyoti Misra
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701226/
https://ncbi.nlm.nih.gov/pubmed/19124718
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