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ICAT expression disrupts β-catenin–TCF interactions and impairs survival of thymocytes and activated mature T cells

T cell factor (TCF) family of transcription factors and β-catenin critically regulate T cell development as demonstrated by the deletion of the tcf gene, which results in a block early in development that becomes complete in mice bearing tcf/lef double deletion. However, the role of β-catenin, a maj...

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Библиографические подробности
Главные авторы: Hossain, M. Zulfiquer, Yu, Qing, Xu, Mai, Sen, Jyoti Misra
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556852/
https://ncbi.nlm.nih.gov/pubmed/18511409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn051
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