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ICAT expression disrupts β-catenin–TCF interactions and impairs survival of thymocytes and activated mature T cells
T cell factor (TCF) family of transcription factors and β-catenin critically regulate T cell development as demonstrated by the deletion of the tcf gene, which results in a block early in development that becomes complete in mice bearing tcf/lef double deletion. However, the role of β-catenin, a maj...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556852/ https://ncbi.nlm.nih.gov/pubmed/18511409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxn051 |
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