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β-Catenin Regulates Positive Selection of Thymocytes but Not Lineage Commitment

Positive selection and lineage commitment to the cytolytic or helper lineage of T cells result in coordinated expression of MHC class I-restricted TCR and CD8 coreceptor or MHC class II-restricted TCR and CD4 molecule. Positive selection signals also regulate the survival and generation of requisite...

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Detalhes bibliográficos
Main Authors: Yu, Qing, Sen, Jyoti Misra
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274003/
https://ncbi.nlm.nih.gov/pubmed/17404285
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