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Molecular basis for the tissue-specificity of β-catenin oncogenesis

Wnt-β-catenin-T Cell Factor signaling is causally linked to c-myc dependent tumorigenesis in mouse and human colon epithelial cells. By contrast, β-catenin is not similarly associated with oncogenic transformation of other tissues, including T cells. The molecular basis for tissue specificity of β-c...

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Detalhes bibliográficos
Main Authors: Sharma, Archna, Sen, Jyoti Misra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534820/
https://ncbi.nlm.nih.gov/pubmed/22689057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.215
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