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Molecular basis for the tissue-specificity of β-catenin oncogenesis
Wnt-β-catenin-T Cell Factor signaling is causally linked to c-myc dependent tumorigenesis in mouse and human colon epithelial cells. By contrast, β-catenin is not similarly associated with oncogenic transformation of other tissues, including T cells. The molecular basis for tissue specificity of β-c...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3534820/ https://ncbi.nlm.nih.gov/pubmed/22689057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.215 |
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