Effect of reducing hypothalamic ghrelin receptor gene expression on energy balance

Central and peripheral injections of Ghrelin potently stimulates food intake via its receptor, GHSR1a expressed in the brain. In this study, we explored the role of GHSR1a in the paraventricular nucleus of the hypothalamus (PVN) by reducing their gene expression using the RNA interference (RNAi). pS...

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Bibliographic Details
Main Authors: Shrestha, Yogendra B., Wickwire, Kathie, Giraudo, Silvia
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700781/
https://ncbi.nlm.nih.gov/pubmed/19540432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2009.03.013
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