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Effects of Hypothalamic Neurodegeneration on Energy Balance

Normal aging in humans and rodents is accompanied by a progressive increase in adiposity. To investigate the role of hypothalamic neuronal circuits in this process, we used a Cre-lox strategy to create mice with specific and progressive degeneration of hypothalamic neurons that express agouti-relate...

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Detalhes bibliográficos
Main Authors: Xu, Allison Wanting, Kaelin, Christopher B, Morton, Gregory J, Ogimoto, Kayoko, Stanhope, Kimber, Graham, James, Baskin, Denis G, Havel, Peter, Schwartz, Michael W, Barsh, Gregory S
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287504/
https://ncbi.nlm.nih.gov/pubmed/16296893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030415
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