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Central Interleukin-1 (IL1) Signaling is Required For Pharmacological, but not Physiological, Effects of Leptin on Energy Balance

Hypothalamic IL1 is suggested to be a critical mediator of the central effects of the adipocyte hormone leptin on energy balance. We hypothesized that IL1 receptor signaling is required for exogenously administered leptin to cause anorexia and weight loss, but not for physiological effects of endoge...

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Detalhes bibliográficos
Main Authors: Wisse, Brent E., Ogimoto, Kayoko, Morton, Gregory J., Williams, Diana L., Schwartz, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706018/
https://ncbi.nlm.nih.gov/pubmed/17320056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.01.073
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