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Central administration of interleukin-4 exacerbates hypothalamic inflammation and weight gain during high-fat feeding
In peripheral tissues, the link between obesity and insulin resistance involves low-grade inflammation induced by macrophage activation and proinflammatory cytokine signaling. Since proinflammatory cytokines are also induced in the hypothalamus of animals placed on a high-fat (HF) diet and can inhib...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904047/ https://ncbi.nlm.nih.gov/pubmed/20371733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00026.2010 |
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