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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells

BACKGROUND: In Arabidopsis thaliana, the gene Tousled encodes a protein kinase of unknown function, but mutations in the gene lead to flowering and leaf morphology defects. We have recently cloned a mammalian Tousled-Like Kinase (TLK1B) and found that it phosphorylates specifically histone H3, in vi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sunavala-Dossabhoy, Gulshan, Li, Yuan, Williams, Briana, De Benedetti, Arrigo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC270066/
https://ncbi.nlm.nih.gov/pubmed/14583098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-4-16
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