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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells
BACKGROUND: In Arabidopsis thaliana, the gene Tousled encodes a protein kinase of unknown function, but mutations in the gene lead to flowering and leaf morphology defects. We have recently cloned a mammalian Tousled-Like Kinase (TLK1B) and found that it phosphorylates specifically histone H3, in vi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC270066/ https://ncbi.nlm.nih.gov/pubmed/14583098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-4-16 |
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