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Chromosomes missegregated into micronuclei contribute to chromosomal instability by missegregating at the next division

Micronuclei (MNi) are extranuclear DNA-containing structures that form upon mitotic exit from unsegregated chromosome fragments or anaphase lagging (whole) chromosomes (LCs). MNi formed from whole chromosomes are of particular interest because LCs are observed in both cancer and non-cancer cells, an...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Bin, Gnawali, Nisha, Hinman, Albert W., Mattingly, Aaron J., Osimani, Alyssa, Cimini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505630/
https://ncbi.nlm.nih.gov/pubmed/31105868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26853
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