Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration

Invariant natural killer T cells (iNKT cells) have pivotal roles in graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effects. iNKT cells are activated through their T-cell receptors by glycolipid moieties (typically the α-galactosylceramide [α-GalCer] derivative KRN7000) presented wi...

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Main Authors: Kuns, Rachel D., Morris, Edward S., MacDonald, Kelli P. A., Markey, Kate A., Morris, Helen M., Raffelt, Neil C., Banovic, Tatjana, Don, Alistair L. J., Rowe, Vanessa, Burman, Angela C., Clouston, Andrew D., Farah, Camile, Besra, Gurdyal S., Illarionov, Petr A., Smyth, Mark J., Porcelli, Steven A., Hill, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700331/
https://ncbi.nlm.nih.gov/pubmed/19369232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183335
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