Identification of distinct human invariant natural killer T-cell response phenotypes to alpha-galactosylceramide

BACKGROUND: Human CD1d-restricted, invariant natural killer T cells (iNKT) are a unique class of T lymphocytes that recognise glycolipid antigens such as α-galactosylceramide (αGalCer) and upon T cell receptor (TCR) activation produce both Th1 and Th2 cytokines. iNKT cells expand when cultured in-vi...

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Autors principals: Croudace, Joanne E, Curbishley, Stuart M, Mura, Manuela, Willcox, Carrie R, Illarionov, Petr A, Besra, Gurdyal S, Adams, David H, Lammas, David A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613383/
https://ncbi.nlm.nih.gov/pubmed/19055753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-9-71
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