Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration

Invariant natural killer T cells (iNKT cells) have pivotal roles in graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effects. iNKT cells are activated through their T-cell receptors by glycolipid moieties (typically the α-galactosylceramide [α-GalCer] derivative KRN7000) presented wi...

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Main Authors: Kuns, Rachel D., Morris, Edward S., MacDonald, Kelli P. A., Markey, Kate A., Morris, Helen M., Raffelt, Neil C., Banovic, Tatjana, Don, Alistair L. J., Rowe, Vanessa, Burman, Angela C., Clouston, Andrew D., Farah, Camile, Besra, Gurdyal S., Illarionov, Petr A., Smyth, Mark J., Porcelli, Steven A., Hill, Geoffrey R.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700331/
https://ncbi.nlm.nih.gov/pubmed/19369232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183335
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