Invariant natural killer T cell–natural killer cell interactions dictate transplantation outcome after α-galactosylceramide administration

Invariant natural killer T cells (iNKT cells) have pivotal roles in graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effects. iNKT cells are activated through their T-cell receptors by glycolipid moieties (typically the α-galactosylceramide [α-GalCer] derivative KRN7000) presented wi...

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Autori principali: Kuns, Rachel D., Morris, Edward S., MacDonald, Kelli P. A., Markey, Kate A., Morris, Helen M., Raffelt, Neil C., Banovic, Tatjana, Don, Alistair L. J., Rowe, Vanessa, Burman, Angela C., Clouston, Andrew D., Farah, Camile, Besra, Gurdyal S., Illarionov, Petr A., Smyth, Mark J., Porcelli, Steven A., Hill, Geoffrey R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700331/
https://ncbi.nlm.nih.gov/pubmed/19369232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-183335
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