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Structural and Dynamic Basis of Phospholamban and Sarcolipin Inhibition of Ca(2+)-ATPase
Phospholamban (PLN) and sarcolipin (SLN) are two single-pass membrane proteins that regulate Ca(2+)-ATPase (SERCA), an ATP-driven pump that translocates calcium ions into the lumen of the sarcoplasmic reticulum, initiating muscle relaxation. Both proteins bind SERCA through intramembrane interaction...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699759/ https://ncbi.nlm.nih.gov/pubmed/18081313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701668v |
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