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Structural topology of phospholamban pentamer in lipid bilayers by a hybrid solution and solid-state NMR method
Phospholamban (PLN) is a type II membrane protein that inhibits the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA), thereby regulating calcium homeostasis in cardiac muscle. In membranes, PLN forms pentamers that have been proposed to function either as a storage for active monomers or as ion channels...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107283/ https://ncbi.nlm.nih.gov/pubmed/21576492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016535108 |
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