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A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints

To fully describe the fold space and ultimately the biological function of membrane proteins, it is necessary to determine the specific interactions of the protein with the membrane. This property of membrane proteins that we refer to as structural topology cannot be resolved using X-ray crystallogr...

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Hlavní autoři: Shi, Lei, Traaseth, Nathaniel J., Verardi, Raffaello, Cembran, Alessandro, Gao, Jiali, Veglia, Gianluigi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824793/
https://ncbi.nlm.nih.gov/pubmed/19597943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9328-9
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