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Disaccharide Analogs as Probes for Glycosyltransferases in Mycobacterium tuberculosis

Glycosyltransferases (GTs) play a crucial role in mycobacterial cell wall biosynthesis and are necessary for the survival of mycobacteria. Hence, these enzymes are potential new drug targets for the treatment of tuberculosis (TB), especially multiple drug-resistant TB (MDR-TB). Herein, we report the...

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Detalhes bibliográficos
Main Authors: Pathak, Ashish K., Pathak, Vibha, Seitz, Lainne, Gurcha, Sudagar S., Besra, Gurdyal S., Riordan, James M., Reynolds, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699567/
https://ncbi.nlm.nih.gov/pubmed/17544276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.04.012
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