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6-Oxo and 6-Thio Purine Analogs as Antimycobacterial Agents
6–Oxo and 6–thio purine analogs were prepared based on the initial activity screening of a small, diverse purine library against Mycobacterium tuberculosis (Mtb). Certain analogs showed moderate to good inhibitory activity. N(9)-substitution apparently enhances the antimycobacterial activity in the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3612542/ https://ncbi.nlm.nih.gov/pubmed/23434367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.01.054 |
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