Antimycobacterial Activities of 2,4-Diamino-5-Deazapteridine Derivatives and Effects on Mycobacterial Dihydrofolate Reductase

Development of new antimycobacterial agents for Mycobacterium avium complex (MAC) infections is important particularly for persons coinfected with human immunodeficiency virus. The objectives of this study were to evaluate the in vitro activity of 2,4-diamino-5-methyl-5-deazapteridines (DMDPs) again...

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Main Authors: Suling, William J., Seitz, Lainne E., Pathak, Vibha, Westbrook, Louise, Barrow, Esther W., Zywno-van-Ginkel, Sabrina, Reynolds, Robert C., Piper, J. Robert, Barrow, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90152/
https://ncbi.nlm.nih.gov/pubmed/10991861
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