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Modular Approach to Triazole-Linked 1,6-α-D-Oligomannosides to the Discovery of Inhibitors of Mycobacterium tuberculosis Cell Wall Synthetase

[Image: see text] Aiming at developing inhibitors of mannosyltransferases, the enzymes that participate in the biosynthesis of the cell envelope of Mycobacterium tuberculosis, the synthesis of a range of designed triazole-linked 1,6-oligomannosides up to a hexadecamer has been accomplished by a modu...

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Detalhes bibliográficos
Main Authors: Conte, Mauro Lo, Marra, Alberto, Chambery, Angela, Gurcha, Sudagar S., Besra, Gurdyal S., Dondoni, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833056/
https://ncbi.nlm.nih.gov/pubmed/20822121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo100928g
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