High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice

BACKGROUND: High-fat diets promote hepatic lipid accumulation. Paradoxically, these diets also induce lipogenic gene expression in rodent liver. Whether high expression of these genes actually results in an increased flux through the de novo lipogenic pathway in vivo has not been demonstrated. METHO...

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Detalhes bibliográficos
Main Authors: Oosterveer, Maaike H., van Dijk, Theo H., Tietge, Uwe J. F., Boer, Theo, Havinga, Rick, Stellaard, Frans, Groen, Albert K., Kuipers, Folkert, Reijngoud, Dirk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699051/
https://ncbi.nlm.nih.gov/pubmed/19557132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006066
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