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High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice

BACKGROUND: High-fat diets promote hepatic lipid accumulation. Paradoxically, these diets also induce lipogenic gene expression in rodent liver. Whether high expression of these genes actually results in an increased flux through the de novo lipogenic pathway in vivo has not been demonstrated. METHO...

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Autori principali: Oosterveer, Maaike H., van Dijk, Theo H., Tietge, Uwe J. F., Boer, Theo, Havinga, Rick, Stellaard, Frans, Groen, Albert K., Kuipers, Folkert, Reijngoud, Dirk-Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699051/
https://ncbi.nlm.nih.gov/pubmed/19557132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006066
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