The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis

BACKGROUND: We previously showed that mice lacking the high mobility group A1 gene (Hmga1-knockout mice) developed a type 2-like diabetic phenotype, in which cell-surface insulin receptors were dramatically reduced (below 10% of those in the controls) in the major targets of insulin action, and gluc...

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Main Authors: Chiefari, Eusebio, Paonessa, Francesco, Iiritano, Stefania, Le Pera, Ilaria, Palmieri, Dario, Brunetti, Giuseppe, Lupo, Angelo, Colantuoni, Vittorio, Foti, Daniela, Gulletta, Elio, De Sarro, Giovambattista, Fusco, Alfredo, Brunetti, Antonio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698822/
https://ncbi.nlm.nih.gov/pubmed/19460132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-7-24
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