Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells

The high-mobility group AT-hook 1 (HMGA1) protein is a nuclear architectural factor that can organize chromatin structures. It regulates gene expression by controlling the formation of stereospecific multiprotein complexes called “enhanceosomes” on the AT-rich regions of target gene promoters. Previ...

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Vydáno v:Front Endocrinol (Lausanne)
Hlavní autoři: Arcidiacono, Biagio, Iiritano, Stefania, Chiefari, Eusebio, Brunetti, Francesco S., Gu, Guoqiang, Foti, Daniela Patrizia, Brunetti, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292585/
https://ncbi.nlm.nih.gov/pubmed/25628604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00237
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