HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway

High-mobility group AT-hook 1 (HMGA1) protein is an important nuclear factor that activates gene transcription by binding to AT-rich sequences in the promoter region of DNA. We previously demonstrated that HMGA1 is a key regulator of the insulin receptor (INSR) gene and individuals with defects in H...

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Main Authors: Chiefari, Eusebio, Nevolo, Maria T., Arcidiacono, Biagio, Maurizio, Elisa, Nocera, Aurora, Iiritano, Stefania, Sgarra, Riccardo, Possidente, Katiuscia, Palmieri, Camillo, Paonessa, Francesco, Brunetti, Giuseppe, Manfioletti, Guidalberto, Foti, Daniela, Brunetti, Antonio
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273854/
https://ncbi.nlm.nih.gov/pubmed/22355763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00251
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