A polymorphism of HMGA1 protects against proliferative diabetic retinopathy by impairing HMGA1-induced VEGFA expression

Diabetic retinopathy (DR) is a major complication of diabetes mellitus, and is the leading cause of blindness in working-age people. Usually, DR progresses from the asymptomatic non-proliferative DR that does not significantly alter vision, to proliferative DR (PDR), which can result in aberrant ret...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Chiefari, Eusebio, Ventura, Valeria, Capula, Carmelo, Randazzo, Giorgio, Scorcia, Vincenzo, Fedele, Monica, Arcidiacono, Biagio, Nevolo, Maria Teresa, Bilotta, Francesco Luciano, Vitiello, Michela, Palmieri, Camillo, Gulletta, Elio, Fusco, Alfredo, Foti, Daniela, Vero, Raffaella, Brunetti, Antonio
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171873/
https://ncbi.nlm.nih.gov/pubmed/27991577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39429
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