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Evaluation of Chlorofusin, its Seven Chromophore Diastereomers, and Key Analogues

Chlorofusin, its seven chromophore diastereomers, and key analogues were comparatively examined for inhibition of MDM2–p53 binding revealing that the chromophore, but not simple replacements, contributes significantly to the natural products properties, and that this contribution is independent of i...

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Autori principali: Clark, Ryan C., Lee, Sang Yeul, Hwang, Inkyu, Searcey, Mark, Boger, Dale L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697908/
https://ncbi.nlm.nih.gov/pubmed/20161293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2009.01.081
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