Pentameric concatenated (α4)(2)(β2)(3) and (α4)(3)(β2)(2) nicotinic acetylcholine receptors: subunit arrangement determines functional expression

BACKGROUND AND PURPOSE: α4 and β2 nicotinic acetylcholine (ACh) receptor subunits expressed heterologously in Xenopus oocytes assemble into a mixed population of (α4)(2)(β2)(3) and (α4)(3)(β2)(2) receptors. In order to express these receptors separately in heterologous systems, we have engineered pe...

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Detalhes bibliográficos
Main Authors: Carbone, A-L, Moroni, M, Groot-Kormelink, P-J, Bermudez, I
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697715/
https://ncbi.nlm.nih.gov/pubmed/19366353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00104.x
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