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Anti-AIDS Agents 72. Bioisosteres (7-carbon-DCKs) of the potent anti-HIV lead DCK
Three 9,10-di-O-(−)-camphanoyl–7,8,9,10-tetrahydro-benzo[h]chromen-2-one (7-carbon-DCK) analogs (3a–c) were synthesized and evaluated for inhibition of HIV-1 replication in H9 lymphocytes. All three new carbon bioisosteres of the anti-HIV lead DCK showed anti-HIV activity. Compound 3a had an EC(50)...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697499/ https://ncbi.nlm.nih.gov/pubmed/17533128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.05.026 |
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