Anti-AIDS agents 87. New bio-isosteric dicamphanoyl-dihydropyranochromone (DCP) and dicamphanoyl-khellactone (DCK) analogues with potent anti-HIV activity

Six 3′R,4′R-di-O-(S)-camphanoyl-2′,2′-dimethyldihydropyrano[2,3-f]chromone (DCP) and two 3′R,4′R-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives were designed, synthesized, and evaluated for inhibition of HIV-1(NL4-3) replication in TZM-bl cells. 2-Ethyl-2′-monomethyl-1′-oxa- and -1′-thia-...

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Detalhes bibliográficos
Main Authors: Liu, Hongshan, Xu, Shiqing, Cheng, Ming, Chen, Ying, Xia, Peng, Qian, Keduo, Xia, Yi, Yang, Zheng-Yu, Chen, Chin-Ho, Morris-Natschke, Susan L., Lee, Kuo-Hsiung
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171603/
https://ncbi.nlm.nih.gov/pubmed/21871800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.07.105
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