Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy

Infectious complications are a major cause of morbidity and mortality from dose-intensive cancer chemotherapy. In spite of the importance of intestinal bacteria translocation in these infections, information about the effect of high-dose chemotherapy on gut mucosal immunity is minimal. We studied pr...

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Detalles Bibliográficos
Main Authors: Xue, H, Field, C J, Sawyer, M B, Dieleman, L A, Baracos, V E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
Assuntos:
Translational Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696758/
https://ncbi.nlm.nih.gov/pubmed/19401694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605051
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