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Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO* and protects mouse embryonic cells against irradiation-induced apoptosis
Generation of reactive oxygen species by damaged respiratory chain followed by the formation of cytochrome c-cardiolipin complex with peroxidase activity are early events in apoptosis. By quenching the peroxidase activity of cytochrome c-cardiolipin complexes in mitochondria, nitric oxide can exert...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696693/ https://ncbi.nlm.nih.gov/pubmed/19427865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.04.050 |
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