A MITOCHONDRIA-TARGETED NITROXIDE/HEMIGRAMICIDIN S CONJUGATE PROTECTS MOUSE EMBRYONIC CELLS AGAINST GAMMA IRRADIATION

PURPOSE: To evaluate the in vitro radioprotective effect of the mitochondria-targeted hemigramicidin S–conjugated 4-amino-2,2,6,6-tetramethyl-piperidine-N-oxyl (hemi-GS-TEMPO) 5-125 in γ-irradiated mouse embryonic cells and adenovirus-12 SV40 hybrid virus transformed human bronchial epithelial cells...

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Bibliografske podrobnosti
Main Authors: Jiang, Jianfei, Belikova, Natalia A., Hoye, Adam T., Zhao, Qing, Epperly, Michael W., Greenberger, Joel S., Wipf, Peter, Kagan, Valerian E.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527544/
https://ncbi.nlm.nih.gov/pubmed/18262096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.10.047
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