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Rh-catalyzed Intermolecular Cyclopropanation with α-Alkyl-α-diazoesters: Catalyst Dependent Chemo- and Diastereoselectivity

[Image: see text] A Rh-catalyzed procedure for the cyclopropanation of alkenes with α-alkyl-α-diazoesters is described. With dirhodium tetraoctanoate, the predominant pathway is β-hydride elimination. While a number of sterically demanding carboxylate ligands serve to avoid β-hydride elimination, it...

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Autors principals: Panne, Patricia, DeAngelis, Andrew, Fox, Joseph M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696156/
https://ncbi.nlm.nih.gov/pubmed/18547051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol800983y
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