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The transcription factors Stat5a/b are not required for islet development but modulate pancreatic β-cell physiology upon aging

In insulinoma cell lines proliferation and insulin gene transcription are stimulated by growth hormone and prolactin, which convey their signals through the transcription factors Stat5a and 5b (referred to as Stat5). However, the contribution of Stat5 to the physiology of β-cells in vivo could not b...

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Bibliografski detalji
Glavni autori: Lee, Ji-Yeon, Gavrilova, Oksana, Davani, Behrous, Robinson, Gertraud W., Hennighausen, Lothar
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695665/
https://ncbi.nlm.nih.gov/pubmed/17599554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.05.010
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