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Leucine-rich repeat kinase 2 mutations and Parkinson’s disease: three questions

Mutations in the gene encoding LRRK2 (leucine-rich repeat kinase 2) were first identified in 2004 and have since been shown to be the single most common cause of inherited Parkinson’s disease. The protein is a large GTP-regulated serine/threonine kinase that additionally contains several protein–pro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Greggio, Elisa, Cookson, Mark R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Neurochemistry 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695577/
https://ncbi.nlm.nih.gov/pubmed/19570025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20090007
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