Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-γ signaling

The control of tyrosine phosphorylation depends on the fine balance between kinase and phosphatase activities. Protein tyrosine phosphatase 1B (PTP-1B) and T cell protein tyrosine phosphatase (TC-PTP) are 2 closely related phosphatases known to control cytokine signaling. We studied the functional r...

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Hauptverfasser: Heinonen, Krista M., Bourdeau, Annie, Doody, Karen M., Tremblay, Michel L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695062/
https://ncbi.nlm.nih.gov/pubmed/19474293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812109106
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