Downregulation of PTP1B and TC-PTP phosphatases potentiate dendritic cell-based immunotherapy through IL-12/IFNγ signaling

PTP1B and TC-PTP are highly related protein-tyrosine phosphatases (PTPs) that regulate the JAK/STAT signaling cascade essential for cytokine-receptor activation in immune cells. Here, we describe a novel immunotherapy approach whereby monocyte-derived dendritic cell (moDC) function is enhanced by mo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Penafuerte, Claudia, Feldhammer, Matthew, Mills, John R., Vinette, Valerie, Pike, Kelly A., Hall, Anita, Migon, Eva, Karsenty, Gerard, Pelletier, Jerry, Zogopoulos, George, Tremblay, Michel L.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486178/
https://ncbi.nlm.nih.gov/pubmed/28680757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1321185
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars