α-Helix targeting reduces amyloid-β peptide toxicity

The amyloid-β peptide (Aβ) can generate cytotoxic oligomers, and their accumulation is thought to underlie the neuropathologic changes found in Alzheimer's disease. Known inhibitors of Aβ polymerization bind to undefined structures and can work as nonspecific aggregators, and inhibitors that ta...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Nerelius, C., Sandegren, A., Sargsyan, H., Raunak, R., Leijonmarck, H., Chatterjee, U., Fisahn, A., Imarisio, S., Lomas, D. A., Crowther, D. C., Strömberg, R., Johansson, J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695042/
https://ncbi.nlm.nih.gov/pubmed/19458258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810364106
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars