Загрузка...
α-Helix targeting reduces amyloid-β peptide toxicity
The amyloid-β peptide (Aβ) can generate cytotoxic oligomers, and their accumulation is thought to underlie the neuropathologic changes found in Alzheimer's disease. Known inhibitors of Aβ polymerization bind to undefined structures and can work as nonspecific aggregators, and inhibitors that ta...
Сохранить в:
| Главные авторы: | , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695042/ https://ncbi.nlm.nih.gov/pubmed/19458258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810364106 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|