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High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors

BACKGROUND: DNA copy number alterations are frequently observed in ovarian cancer, but it remains a challenge to identify the most relevant alterations and the specific causal genes in those regions. METHODS: We obtained high-resolution 500K SNP array data for 52 ovarian tumors and identified the mo...

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Hlavní autoři: Haverty, Peter M, Hon, Lawrence S, Kaminker, Joshua S, Chant, John, Zhang, Zemin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694826/
https://ncbi.nlm.nih.gov/pubmed/19419571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-21
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