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High-resolution mapping of copy-number alterations with massively parallel sequencing
Cancer results from somatic alterations in key genes, including point mutations, copy number alterations and structural rearrangements. A powerful way to discover cancer-causing genes is to identify genomic regions that show recurrent copy-number alterations (gains and losses) in tumor genomes. Rece...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630795/ https://ncbi.nlm.nih.gov/pubmed/19043412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1276 |
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