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Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing
Our variant ascertainment algorithm VAAL uses massively parallel DNA sequence data to identify differences between bacterial genomes at high sensitivity and specificity. VAAL found ~98% of differences (including large indels) between pairs of strains from three species while calling no false positiv...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613166/ https://ncbi.nlm.nih.gov/pubmed/19079253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1286 |
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