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Massively parallel discovery of human-specific substitutions that alter enhancer activity
Genetic changes that altered the function of gene regulatory elements have been implicated in the evolution of human traits such as the expansion of the cerebral cortex. However, identifying the particular changes that modified regulatory activity during human evolution remain challenging. Here we u...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812811/ https://ncbi.nlm.nih.gov/pubmed/33372131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007049118 |
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