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Massively parallel discovery of human-specific substitutions that alter enhancer activity
Genetic changes that altered the function of gene regulatory elements have been implicated in the evolution of human traits such as the expansion of the cerebral cortex. However, identifying the particular changes that modified regulatory activity during human evolution remain challenging. Here we u...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812811/ https://ncbi.nlm.nih.gov/pubmed/33372131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007049118 |
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