Multigene amplification and massively parallel sequencing for cancer mutation discovery

We have developed a procedure for massively parallel resequencing of multiple human genes by combining a highly multiplexed and target-specific amplification process with a high-throughput parallel sequencing technology. The amplification process is based on oligonucleotide constructs, called select...

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Main Authors: Dahl, Fredrik, Stenberg, Johan, Fredriksson, Simon, Welch, Katrina, Zhang, Michael, Nilsson, Mats, Bicknell, David, Bodmer, Walter F., Davis, Ronald W., Ji, Hanlee
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871563/
https://ncbi.nlm.nih.gov/pubmed/17517648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702165104
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