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Analysis of DNA Copy Number Alterations in Ovarian Serous Tumors Identifies New Molecular Genetic Changes in Low-grade and High-grade Carcinomas

Ovarian serous carcinoma, the most common and lethal type of ovarian cancer, was thought to develop from two distinct molecular pathways. High-grade (HG) serous carcinomas contain frequent TP53 mutations while low-grade (LG) carcinomas arise from serous borderline tumors (SBT) and harbor mutations i...

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Detalhes bibliográficos
Main Authors: Kuo, Kuan-Ting, Guan, Bin, Feng, Yuanjian, Mao, Tsui-Lien, Chen, Xu, Jinawath, Natini, Wang, Yue, Kurman, Robert J., Shih, Ie-Ming, Wang, Tian-Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782554/
https://ncbi.nlm.nih.gov/pubmed/19383911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3913
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