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Lipophilicity of potent porphyrin-based antioxidants. Comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins

Mn(III) N-alkylpyridylporphyrins are among the most potent known SOD mimics and catalytic peroxynitrite scavengers, and modulators of redox-based cellular transcriptional activity. In addition to their intrinsic antioxidant capacity, bioavailability plays major role in their in vivo efficacy. While...

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Bibliografiske detaljer
Main Authors: Kos, Ivan, Rebouças, Júlio S., DeFreitas-Silva, Gilson, Salvemini, Daniela, Vujaskovic, Zeljko, Dewhirst, Mark W., Spasojevic, Ivan, Batinic-Haberle, Ines
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694496/
https://ncbi.nlm.nih.gov/pubmed/19361553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.04.002
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