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Seeding and Propagation of Untransformed Mouse Mammary Cells in the Lung

The acquisition of metastatic ability by tumor cells is considered a late event in the evolution of malignant tumors. We report that untransformed mouse mammary cells that have been engineered to express the inducible oncogenic transgenes MYC and Kras(D12), or polyoma middle T, and introduced into t...

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Detalhes bibliográficos
Main Authors: Podsypanina, Katrina, Du, Yi-Chieh Nancy, Jechlinger, Martin, Beverly, Levi J., Hambardzumyan, Dolores, Varmus, Harold
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694414/
https://ncbi.nlm.nih.gov/pubmed/18755941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1161621
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