Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models

We have adapted the avian leukosis virus RCAS (replication-competent avian sarcoma-leukosis virus LTR splice acceptor)-mediated somatic gene transfer technique to introduce oncogenes into mammary cells in mice transgenic for the avian subgroup A receptor gene, tva, under control of the mouse mammary...

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Main Authors: Du, Zhijun, Podsypanina, Katrina, Huang, Shixia, McGrath, Amanda, Toneff, Michael J., Bogoslovskaia, Ekaterina, Zhang, Xiaomei, Moraes, Ricardo C., Fluck, Michele, Allred, D. Craig, Lewis, Michael T., Varmus, Harold E., Li, Yi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635021/
https://ncbi.nlm.nih.gov/pubmed/17090666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608607103
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